afirma gsc suspicious 50
I find out my biopsy results next week. I'm also anxiously waiting my pathology results! Surgical margins: negative for tumor (tumor is < 0.1cm from margin) A test with a better NPV (negative predictive value), would be more usefu than ever in that situation. . This occurs in 1520% of biopsies and often results in the need for surgery to remove the nodule. The Annual International Thyroid Cancer Survivors' Conference and Regional Workshops, Download our free Low-Iodine Cookbook (PDF), Rally for Research and Thyroid Cancer Research Grants. they misclassify benign nodules as suspicious! The .gov means its official. 1. Thyroid bloodwork normal. She then tells me that at a recent conference, there was a lot of discussion of Afirma, and the general consensus seemed to be that it was good at detecting papillary cancer, but not necessarily follicular. One > 2cm, undetermined twice and "suspicious for follicular neoplasm" the most recent FNA On cytologic evaluation 3.0% of the cases were non diagnostic (ND), 9% benign, 62% AUS, and 26% suspicious for neoplasm (SN). I'm shocked that my voice is still completely in tact. Conversely, when evaluating nodules with suspicious molecular testing, surgical rates were 88% and 89%, respectively, for GEC and GSC (P = 0.853) . The aggressive one wants to cover his ass in the tiny chance you have an aggressive thyroid cancer, and the wait and see one is playing the odds that there is nothing to worry about, and that unneeded surgery has risks that are higher than the benefits in your case. Of the 164 nodules included in the study with the GSC test, suspicious nodules were found in 39 of the 164 nodules (23.7%). Here are some results/Info: And she said her surgeon said that this test is not very reliable and that meanwhile she has a large bill from the company. Which means I would still be paying this amount to the hospital if I didn't pay it to Affirma. The GSC incorporates nuclear and mitochondrial RNA transcriptome gene expression, RNA sequencing, and genomic copy number analysis. Afirma testing is back "Risk of malignancy: Afirma GSC Suspicious ~50%" "Malignancy classifiers: Negative" "MTC and BRAF classifier results were negative and RET/PTC1 and RET/PTC3 were not detected. My Endo thinks I should see a thyroid surgeon and my other doctor wants to repeat ultrasounds in 4 months, adopting a wait and see approach. eCollection 2021 Nov 1. Nevertheless, I am reluctant to just proceed particularly for the following reasons: government site. I am very resistant to the thought of having a gland removed that is functioning perfectly fine, if it isn't cancer. So, in 2014, Thanksgiving was about telling them there was something going on. https://www.inspire.com/groups/thyca-thyroid-cancer-survivors-association/discussion/need-advice-surgery-or-not-based-on-40-afirma-test/?page=2#replies. It was found incidentally in an MRI I had for cervical spine pain. Background: The Afirma Gene Expression Classifier (GEC) has been used to further characterize cytologically indeterminate (cyto-I) thyroid nodules into either benign or suspicious categories. So frustrating!! I am so new to all this that I don't know what this means. http://onlinelibrary.wiley.com/doi/10.1002/cncy.21455/full. But in my case, it was a risk well worth taking. Recommended surgery for suspicious cancer cells. My surgeon wants to operate right away stating that these kind of results have a 90% truancy for cancer to be present. Method: The Affirma Genomic Sequence Classifier (GSC) is based on DNA sequencing. http://www.glandsurgery.org/article/view/1002/1193 Biotech Strategy Blog in this post by Pieter Droppert June 28,2012 Also mentions 48% of nodules falsely called "suspicious" for cancer and can cause many people to have unnecessary thyroid surgery when they don't have cancerous thyroid cells! I pointed out to them that since the nodule tested was less than 1cm the radiologist should not have sent it and they should not have tested it. I had a biopsy for 4 nodules 2 mos ago. http://biotechstrategyblog.com/2012/06/veracyte- afirma-gene-expression-classifier-thyroid-cancer- diagnostic-test.html/ I'm sure that over the years as more people have this Afirma test done,there will be even more people posting on thyroid and general health boards about getting false "suspicious" results from it! Background: The Afirma MTC may not be billed separately using an additional unit or procedure code. Treatment like a cytologically benign nodule may be appropriate, including clinical correlation. o The Afirma MTC testing must be billed as part of the Afirma GSC. See Somatic Mutation Testing - Solid Tumors guideline for criteria. I was doing some research and came across the Afirma Thyroid Analysis by Veracyte and was wondering if anyone in a similar situation had tried this and what there results were. But, I'm also tired of living with the uncertainty and semi-annual nerve sessions after each ultrasound. The cancer-associated genes important in thyroid cancer are BRAF, RET/PTC and RAS. I don't know if I'm speaking too soon, but the pain isn't as bad as I thought it would be. B. https://www.inspire.com/groups/thyca-thyroid-cancer-survivors-association/discussion/genetic-test-two-different-results/reply/6888430/?msg_activity=reply_posted. So, if you were going to go down that route then this will save you from having a second biopsy. the nodule was only 1.5 cm and I really had no concerning symptoms. I understand that Afirma tends to have a lot of false positives, but it's supposed to be fairly accurate for negative results. Another problem with Afirma is that pretty soon they are going to have to adjust the test to the reclassification of non-invasive FVPTC. I opted for a total after much thought because I had three un biopsied nodules on the other side and was already hypo with my entire thyroid to begin with. After reading many stories, I didn't know what to expect. They were incredibly supportive and also concerned. The site is secure. I immediately started crying, knowing that a phone call wasn't "the good news." Please, I am looking for any and all thoughts. I had the ultrasound, and am waiting for my appointment with her to go over the images. Please Help! 2021 May 13;12:649522. doi: 10.3389/fendo.2021.649522. sharing sensitive information, make sure youre on a federal My thyroid nodule (1.5 cm) was discovered by mistake; the technician was only supposed to do an ultrasound on my gallbladder and ovaries, but for some reason did my thyroid as well. However, FVPTC is currently classified as a type of "papillary" carcinoma, so the rate of diagnosis is also going to fall pretty substantially. The . So I gather if I am reading what you reported correctly, your case is another false NEGATIVE for the Afirma test? Also difficult is the reaction from others. I have also read a recent 2015 report that posits that there are built-in subjectivities to begin with at the Ultrasound/Pathology level yielding "Indeterminate" or "Atypical Cells" to begin with that then sets up a natural path to getting a "Suspicious" result from Afirma. I have bumps on my head that come and go and are considered normal, and another cyst on my arm that I've had since I was eleven -- also normal. Afirma BRAF V600E o Afirma BRAF testing may be considered for either GSC or FNA suspicious or malignant results. It's pretty difficult being the patient trying to sort this all out. Without my permission my specimen was sent to Affirma and their results were Benign, so my radiologist amended her results to benign for all 4 nodules. (And myself.) 1). Multiple nodules. The authors reported the following rates of final diagnoses for these specimens: 65% of cases had no cancer (ie. Multiple nodules. Negative for BRAF, RET/ptc1 and ptc3 Epub 2020 Aug 6. Mild lymphocytic thyroiditis ( nonspecific) That not only had the nodule continued to grow (from 2.0 to 3.2cm over the last 2 years), but it is now showing increased central vascularity. suspicious - ~50% risk of cancer. Hi, He recently emailed me back and said,as we discusssed on the phone,he agrees with many of my concerns about the Afirma test. 2. o The Afirma MTC testing must be billed as part of the Afirma GSC. Good luck and happy thoughts! I'm a foodie who has always struggled with weight, but I also exercise so I'm always just plump but in otherwise decent health. http://www.glandsurgery.org/article/view/1002/1193, http://biotechstrategyblog.com/2012/06/veracyte-, Papillary and follicular thyroid cancer (differentiated), Multiple endocrine neoplasia type 2 (MEN2), Mental challenges of living with thyroid cancer, ThyCa fundraising and thyroid cancer research grants. Home Patients Portal Clinical Thyroidology for the Public October 2016 Vol 9 Issue 10 p.11-12, CLINICAL THYROIDOLOGY FOR THE PUBLIC Most probably, a lot more lobectomies are going to be performed for indeterminate nodules since the level of certainty is going to drop. The result of this 2.1 cm Bethesda IV nodule A is Arma GSC Benign, which suggests a low risk of cancer at approximately 4%. Have lots of decisions to make and just trying to do some homework. It is unclear whether mutations in these genes cause the cancer or are just associated with the cancer cells. So we decided to remove the right lobe a week after the afirma results. I also recently found *another* article written by an endocrine surgeon Sam Wiseman from the Department of Surgery ,St.Paul's Hospital University Of British Columbia for the site Gland Surgery where he also points out real concerns that half of patients(as I said I know it's more,from all of the people I have found posting on thyroid boards) with benign nodules wrongly classified as "suspicious" by the Afirma test are getting unnecessary thyroid surgery because this Afirma result influenced a lot of endocrinologists and their patients to have the thyroid surgery! I had my surgery in NYC, it took 2 hours, and I went home the same day. My question is then I guess, is it really that bad afterwards managing levels and the other side effects post TT? I had that one sent to Afirma, and it came back indeterminate on cytopathology again, benign on GEC. -Lymph Node US: Mostly clear in neck, 1 ovoid focus in submandibular region that may be enlarged LN or Submandibular Lesion The authors concluded that a GEC suspicious test result may include noninvasive follicular variant papillary thyroid cancer as well as classical papillary thyroid cancer. I have found this community very informative, thank you. I am so glad to find this as reading everyone's story helps me feel not so aloneTHANK YOU! Suspicious readings of the Afirma gene-expression classifier include some noninvasive encapsulated follicular variant of papillary thyroid carcinomas BACKGROUND Thyroid nodules are commonly found on ultrasound of the neck and the evaluation of a thyroid nodule may include thyroid biopsy. Each of my pre-surgical tests are pointing more and more in the wrong direction. Wow! Molecular testing for indeterminate thyroid nodules: Performance of the Afirma gene expression classifier and ThyroSeq panel. I asked him if I could get another opinion on my FNA slides and he said yes and I asked him who he could recommend that is very good with thyroid pathology and FNA's and he recommended quite a few Dr.'s so I asked about any at The Mayo Clinic where he used to work and did that Afirma study from,and he recommended three Dr.'s there. Suspicious Nodule Surgery the Only Option? They did not address that issue in their letter, just my income. Two have been tested by FNA multiple times over 5 years We had a long talk and discussed more conservative options, like a partial thyroidectomy, but no rush. WHAT ARE THE IMPLICATIONS OF THIS STUDY? Several thyroid nodules. National Library of Medicine t=5283], http://www.thyroidboards.com/showthread.php? Afirma; FNA; cytology; thyroid nodules. Here is what the Affirma test disclaimer said: Benign: Preformance characteristics not defined for nodules less than 1 cm diameter. The two types that are set to be reclassified are the non invasive encapsulated type and the non invasive unencapsulated type. I was told the only way to find out for sure is to have half my thyroid removed. I had numerous FNA biospy's last result "suspicious for follicular neoplasm " , the last ultrasound showed several microcalcifications on left and scattered microcalcification on the right. I didn't make a big deal about the cost because I am having surgery and they money I paid was my 20% co-pay and my out of pocket limit is almost met. The remaining 18% were malignant. Thyroid. I had another biopsy which came back showing "Atypical cells". 5. SUMMARY OF THE STUDY Advice needed please. I'd done enough research to know that Thyroid cancer is generally treatable, and was sure to tell them about that. Ultrasound reports unfortunately not very informative other than size. This was done in hopes of maintaining my own thryoid function which the doctors and I felt better than taking thyroid medicine daily for the rest of my life. Cancer-Associated Genes: these are genes that are normally expressed in cells. Afirma said NEGATIVE for BRAF and Meduliary but still assigned a classification of "Suspicious" with 40% chance of cancer. This isn't saying that Afirma's test isn't useful. Thanks for chiming in. These gene patterns are better at ruling out thyroid cancer in an indeterminate nodule than confirming cancer. Genes hold the information to build and maintain an organisms cells and pass genetic traits to offspring. And the 3rd test was Afirma which came back "suspicious". BACKGROUND Fingers crossed they come back negative for cancer! Gorshtein A, Slutzky-Shraga I, Robenshtok E, Benbassat C, Hirsch D. Eur Thyroid J. What was your experience? Only when I had a follow up visit with a cardiologist in JAn.of 2016 he noticed the results after requesting the previous scan results. The rate of malignancy in nodules suspicious for neoplasm (SN) on cytology interpretation was 31.2% (5/16). Thyroid nodules are very common, occurring in up to 50% of individuals. I almost want to cancel the surgery. I'm a lumpy person, I told my husband. http://www.thyroidboards.com/showthread.php? I have slightly high blood pressure and slightly high cholesterol that are well controlled with meds. And she's just mostly silent about it. malignant - The chance of cancer is very high >99% malignancy, surgery is necessary. Our new findings show that the real-world experience supports this data, further demonstrating that the likelihood of malignancy in Afirma GSC-suspicious nodules is even greater than what was . The panel includes genes that have been identified So far, no problems with calcium. There was no follow up in 13% of cases and 87% were resected (50% lobectomies and 50% total thyroidectomies). I have made an appointment with another endocrinologist, but just to talk to him. The cells need to be "fresh." There are 3 variants of papillary thyroid cancer: classic, follicular and tall-cell. Can someone give me their take on my fna results? I've read a lot about this test (both good and bad). My oldest daughter has a friend who has survived thyroid cancer, and SHE was sure to tell ME about that. Each wait has been tough, but the wait after the biopsy was excruciating. SUMMARY OF THE STUDY Before Follicular and hurthle cells are normal cells found in the thyroid. It is illegal for auto mechanics to do work on our car without an estimate, or accountants, lawyers etc but doctors and medical facilities can just run us into BK without any regard. Incidental papillary thyroid carcinoma, .2 cm on Left lobe and Thyroid right lobe: 1.2 cm nodule-Papillary thyroid carcinoma, conventional and follicular variant, histologically infiltrating into adherent skeletal muscle: .2 cm and the right lobe: 1.4 cm, both 2021 Oct 7;5(11):bvab148. FOIA Thus, 54 NIFTP cases were established, all with a suspicious Afirma GEC result. Endo M et al 2019 Afirma Gene Sequencing Classifier compared with Gene Expression Classifier in indeterminate thyroid nodules. These results do not change the risk of malignancy of the (ROM) of the Afirma GSC suspicious result." I called back and left them a message that was at home, to call me back. The mindset of medical doctors is to analyze the information at hand and see if anything changes that warrants getting more data or doing surgery.". She also said that her endo said that all of his colleagues stopped using this test and that in their experience the number of suspicious that came back cancerous is the same as what you find in the general population. Epub 2021 Jun 22. These results show an improved accuracy for the GSC as compared with the GEC. But it is saying that actual surgical results show that 40% "suspicion" turns out to send lots of people to surgery and then about 50% of the surgeries done yield results that show that the nodules were not cancerous at all. Of the 343 nodules that underwent the GEC test, 178 cases (51.9%) were considered suspicious for cancer. The surgeon was great. Historically, most patients with indeterminate thyroid nodule biopsies were referred for surgery though most would ultimately not have thyroid cancer (around 75% or more would have an unnecessary surgery). The https:// ensures that you are connecting to the All thyroid nodules with a "suspicious" Afirma GEC result were investigated. The main goal was to help decide if my "suspicious for neoplasm" nodule was benign or not. I do not have calcifications but all 4 nodules are solid, hypoechoic and vascular. Thyroid cancer is found in ~5% of thyroid nodules, so the vast majority are benign (noncancerous). Thyroid 2016;26:911-5. Please let me know what you think. Anyone have AUS nodule with suspicious Afirma results end up cancerous? This process has helped me to realize that there is a lot that physicians do not understand--much more than I knew. -5.5cm x 3.9cm x 3.9cm Left Thyroid Nodule: Large mixed/mostly solid, isoechoic, ill-defined margins, macrocalcifications, taller-than-wide: TI-RADS 5 You cannot become a thyroid cancer specialist in 24 hours needless to say. Euphemia I just read your post about classifications changing. And is this what that recent October 2015 WSJ article was hinting at.having people with certain types of cancer of the thyroid not undergo surgery at all but just adopt a wait and see posture? My expensive, unsolicited, Afirma test results came back as negativegood thing I had already had my TT before I received the results; I have stage III pap/follicular thyca. 3. This study suggests that more research is needed to determine if the noninvasive follicular variant thyroid cancer can be diagnosed by molecular markers without proceeding to surgery. undefined will no longer be visible to you including posts, replies, and photos. Her only information about this comes from me, as she lives across the country and can't go to doctor's visits with me. The current Afirma Genomic Sequencing Classifier (GSC) demonstrates improved specificity, suggesting more nodules will have a benign result (benign call rate [BCR]), but independent data are needed to confirm this in clinical practice. Is is the Benign that is a false negative ? False positive rate of Afirma was 56% (32/57). I opted to have the TT and it turned out it was cancerous and had spread to a few lymph nodes, so then I had right and left central neck dissections as well. Mine did, and that can also be a sign of cancer. This all new to me and I have a lot to learn. I've been battling hypothyroidism and suspicious thyroid nodules for 4 years. The Afirma Genomic Sequencing Classifier (GSC) result was "Suspicious," but the usual orange color (representing ~50% risk of malignancy) of this result is replaced with gray, foreshadowing that . Papillary thyroid carcinoma, Follicular Variant, 2.1 cm in greatest dimension, present in mid to lowe pole, woth prior FNA site changes. Personally, I think getting the AFIRMA test done is a good thing. She also said that her surgeon told her he's had five patients that had a suspicious result from the Afirma test,and then when their nodules were removed and tested they too were benign! The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). The doctor uses a very thin needle to withdraw cells from the thyroid nodule. Meanwhile I read a recent WSJ article about patients with ACTUAL thyroid cancer being offered a wait and see approach as there are so many issues after surgery--not just discomfort issues like fatigue, weight gain and so forth but also secondary cancers. What have been your experinces with AFIRMA? The doctor uses a very thin needle to withdraw cells from the thyroid nodule. But still my labs are all within normal range. My AFIRMA is also 40% risk. I was told my path report from the local hosp was inconclusive so it had to be sent to Mayo Clinic and after almost three weeks after my surgery, I got the word that it was cancerous. A 36% Increase in Specificity With Afirma GSC Versus Older Test . 2016 Jul;26(7):911-5. doi: 10.1089/thy.2015.0644. I had a lobectomy sep. 30th. The Afirma GSC is designed to help clinicians manage these patients. A publication of the American Thyroid Association, Summaries for the Public from recent articles in Clinical Thyroidology, Table of Contents | PDF File for Saving and Printing, THYROID CANCER Of the 16 cases of follicular variant papillary thyroid cancer, 14 of them were noninvasive follicular variant of papillary thyroid cancer (88%). The Afirma Genomic Sequencing Classifier (GSC) provides physicians with a comprehensive solution for a complex landscape in thyroid cancer diagnosis and individualization of care. The other tested indeterminate, follicular atypia, cannot rule out follicular neoplasm. He later called and said he was sending me for a biopsy. You started down the rabbit hole by focusing on your thyroid gland for no good reason, since the melanoma is not related to anything regarding your asymptomatic thyroid. I hadn't told my two college-age daughters about the series of more and more concerning doctor's visits, but knew I couldn't get through a long day with them at home without showing my emotions. benign), 25% of cases had follicular variant papillary thyroid cancer, 2% of cases had classical papillary thyroid cancer and 8% of cases had follicular thyroid cancer. I've read a lot about this test (both good and bad). I did not get to go under the knife for my TT til this past March. They incidentally found a nodule on my right thyroid tru CTSCAN in Dec.2014. At first it sounded like only the encapsulated variety was going to be included in the reclassification, but more recently it seems that non-encapsulated and non-invasive FVPTC is also going to be included. Clipboard, Search History, and several other advanced features are temporarily unavailable. But, I am concerned about the report I just received. Afirma BRAF V600E o Afirma BRAF testing may be considered for either GSC or FNA suspicious or malignant results. 2018 Jul;126(7):471-480. doi: 10.1002/cncy.21993. 2017;45:308-311. I agree that you should have been consulted for the genetic test!! My Afirma results came back suspicious. BACKGROUND The doc mentioned the thyroid and upon a physical exam felt the nodule, leading to the rest of the testing. Wong KS, Angell TE, Strickland KC, Alexander EK, Cibas ES, Krane JF, Barletta JA. That was a hard Thanksgiving. This did not surprise me since I had researched "suspicious." Used for FNA indeterminate nodules (bethesda III-IV). He is very calm and laid back, and prefers to take a more controlled approach to everything, but I'm feeling a more aggressive approach is warranted. I am scheduled to have a TT on March 9th and I wish I felt a little better about my decision. Noninvasive follicular variant of papillary thyroid carcinoma and the Afirma gene-expression classifier. They call follicular neoplasms with hurthle cells FNOF. And it keeps growing. Results: A publication of the American Thyroid Association, Suspicious readings of the Afirma gene-expression classifier include some noninvasive encapsulated follicular variant of papillary thyroid carcinomas. I am also concerned about hormone replacement, would like some personnal comments on recovery from Lobectomy versus TT . Second, this nodule has been stable and has not grown from the first day it was discovered. 2.) I don't think the reclassification was mentioned specifically in the WSJ article. My blood tests came back totally normal and I am totally asymptomatic. When the nurse called she couldn't even tell me results over he phone -- she said she didn't know them -- but set up an appointment for end of the following week -- another wait. I'm fearful this is a Hurthle Cell Lesion, and I do not like what I have read. On this topic from this forum member bmcm2girls said she too had a false suspicious result from the Afirma test and her nodule was benign when removed. This study investigated the outcome of the thyroid nodules deemed to be "suspicious" by the Afirma GEC in a high risk population. A thyroid nodule biopsy can be benign (normal), malignant (cancer) or indeterminate. ThyCa: Thyroid Cancer Survivors' Association, Inc. Neither will talk to the other. I'm a 39 years old male. My doctor then sent me to an endocrinologist for a biopsy which came back with atypical but inconclusive results. Thanks. I'm afraid I feel ok now then all of a sudden will begin feeling horrible. I was seen by a thryoid surgeon who did a 1st biopsy with w/ " suspicious of FVPTC". No it's actually the opposite.Many studies by different endocrinologists that were published in The American Thyroid Association's Journal in 2012 found that only 4% of the time the Afirma test falsely says cancerous nodules are benign but it falsely calls benign nodules ''suspicious'' at least 48% of the time! Dr.Hershman then says, In a world where there are unlimited financial resources,both the oncogene and the GEC methods could be applied to all indeterminate nodules,but this approach is not practical currently. My Afirma results also came back as "suspicious." Thyroid Nodules: http://www.thyroid.org/thyroid-nodules/, Thyroid Cancer: http://www.thyroid.org/thyroid-cancer/, Thyroid Surgery: http://www.thyroid.org/thyroid-surgery/. There are risks and benefits to any decision - and humans are very bad at assessing both. Maternal side history of goiter in females, no known thyroid cancer, but late breast cancer and colon cancer Patients with thyroid nodule biopsies with indeterminate cytology results were chosen for additional genetic testing; the Afirma GEC (during the period February 2, 2011July 11, 2017) or the Afirma GSC (during the period July 11, 2017December 19, 2018). A group of expert pathologists have recently identified a subgroup of papillary thyroid cancer called noninvasive follicular variant papillary thyroid cancer that has a very low risk of relapsing after surgical removal. Can you expand on this? I'm looking for any and all help and/information you can share with me. An important limitation of this study is that the authors did not examine the rate of noninvasive follicular variant papillary thyroid cancer in specimens that were not reported as suspicious by the GEC test. As I have learned on this board, just 'taking a pill' for the rest of your life isn't as easy as it sounds. The Afirma GSC is a cancer rule-out test with a high negative predictive value so that cytologically indeterminate (Bethesda III/IV)2thyroid nodules with an Afirma GSC benign result can be considered for clinical observation in lieu of diagnostic surgical resection (Fig. Please click on this link below about the woman with a 1-1 and half cm solid hypoechoic nodule who had an inconclusive Fine Needle biopsy which was suspicious as a follicular neoplasm and mine is being called a follicular neoplasm with oncocytic (hurthle cell features) ,this woman had her FNA nodule sample tested by the veractye Afirma Test which is what I had done,the results came back telling her that her that their results on her FNA was highly suspicious and that because of this her endo told her she had an 80% chance of having thyroid cancer and so she had her thyroid out and found out it was benign! For nodules determined to be GSC Suspicious or with a cytopathology diagnosis of Bethesda V or VI, physicians ordered XA by checking a box. I wish you luck in whatever you decide. Many endocrinologists have written articles in The American Thyroid Association's journal criticizing the inaccuracies and unrelabilities of this recent Afirma test, the strongest criticism and concern is by endocrinologist of (*50* years!) I didn't want to live with the risk, especially already being hypo and having nodules on the other side slowly growing. This test is performed by the company Veracyte Inc. BACKGROUND Thyroid nodules are very common, occurring in 30-50 % of patients. Thyroid Fine Needle Aspiration Biopsy (FNAB): Change In Thyroid Nodule Volume Calculator, Find an Endocrinology Thyroid Specialist, Clinical Thyroidology for the Public (CTFP). Would you like email updates of new search results? Molecular markers can be used in thyroid biopsy specimens to either to diagnose cancer or to determine that the nodule is benign.
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